Take off to want:Purpose:Observe 100 apoplexy sufferers applies thunder Ni to substitute D to the prevention function which erupts to bleed up the digest way.Method:The foundation cured in the normal regulations up add to use thunder Ni to calm down for the D 100 mgs drop, everyday 1~2 times, total 2 weeks, the in the interval observation is relevant up digest way bleed of index sign and to ill rate etc. of influence.Result:Treatment set and matched control erupt to expect the death rate to distinguish to 2%, 18% and 19.2%, 32.6% up digest way incidence rate and acute for bleed.(P<0.01)Conclusion:The thunder Ni substitutes D and can not only obviously lower an apoplexy to erupt an incidence rate for bleed up the digest way, but also can improve acute to expect of prepare behind.
Keyword: The thunder Ni substitutes D; Apoplexy; Last the digest way bleed
Observe the Function of Ranitidine in Preventing Cerebral Hemorrhage that Complicate Stress Ulcer by Observing 100 cases
Abstract: Objective: The hemorrhage.Method of the in cerebral of the gastrointestinal hemorrhage of the of upper of the on preventing of the of Ranitine of the efficency of the To study: 100 patients with cerebral hemorrhage received Renitidine 100 mg ivgtt gd or bid for 14 dags on the base of convent ional treatment anel obser vef the relative variables anel the effluence to ratal rate. Result: The uncidence rate and ratal rate during the acute time of the therapeutic group anal control group that complicate the upper gastrointestinal hemorrhage is 2%, 18% ands be 19.2%s, 32.69%.(p<0.01)Conclusion: Ranutudune not only can decrease the ratal of upper gastroinrestinal which is the complication of cerebral hemorrhage but also in proving the progrosis significantly during the acute time.
Key words: Ranitidine; Cerebral hemorrhage; Upper gastrointestional hemorrhage
Apoplexy’s erupting and should arouse sex ulcer to pay a digest way issue of blood is a kind of familiar but serious complications, main performance in order to throw up blood, black then or both and have, the condition is more heavy, the incidence rate is more high, and having a cultural heritage report a way its incidence rate can reach to 19.4% ［s with 48.28% ～s one ］ .And the top digest way bleed more and early, more bad after prepare, my hospital application the thunder Ni prevents apoplexy from erupt bleed up the digest way for the D and obtained satisfied effect.
One material and method
1.1 clinical data:Is divided into the 204 principle methods with random basis of apoplexy sufferer which confirm through the CT check the prevention treatment set(normal regulations treatment+prevention treatment) and normal regulations treatment set.(only use a normal regulations treatment)Should arouse sex ulcer to appear to vomit a coffee kind thing after diagnose mainly according to the outbreak, with(or) solution asphalt kind move bowels, vomit a thing with or move bowels concealed blood experiment masculine gender.The treatment set is 100, male’s 53, female’s 47, the age is 44~78 years old, average(58.1 ±s be 7.79 years old), among them, the base stanza area apoplexy is 53 and the base stanza-Qiu brain area apoplexy is 27 and the brain leaf bleeds 7 and the Qiu apoplexy is 5 and the brain stem bleeds 3, the small poplexy is 3, and the brain room bleeds 2.The normal regulations treatment set is 104, male’s 59, female’s 55, the age is 48~81 years old, average(58.9 ±s be 8.15 years old), among them, the base stanza area bleeds 56 and the base stanza-Qiu brain area apoplexy is 24 and the brain leaf bleeds 13 and the Qiu apoplexy is 4 and the brain stem bleeds 3, the small poplexy is 2, and the brain room bleeds 2.
1.2 methods
1.2.1 normal regulations treatment set:The normal regulations treatment includes control blood pressure, control brain dropsy, lower to press inside Lu and maintain water electrolyte balance, support an etc. treatment to the disease, 14 ds for 1 treat a distance.
1.2.2:Normal regulations treatment+prevention treatment, at normal regulations treatment the foundation of the set up, all while starting cure add to use thunder Ni substitute the D 100 mgs, everyday 1~2 times join in 10% glucoses quiet drop, 14 ds for 1 treat a distance.Two sets of sufferers are in the process of cure in all and strictly control food, forbid a carnivorous type, and forbid to use vitamin C at least a 2 ds is above.
1.3 covariances learn analysis:Adopt card a square an examination.
2 results
2.1 rightnesses of prevention functions for bleed, :Through cure 1 treats after the distance the last digest way to bleed of see table as a result 1.
Form 1 two sets of sufferers erupt the comparison for bleed up the digest way(slightly)
Note:Two sets of comparison Ps<0.01
2.2 rightnesses of influences which prepare behind:At impatient period treatment set death up 18(18%), the matched control dies 34(32.69%), set have to show Zhao difference than the effect.(P<0.01)Survival the different degree be partial to Tan to lose language, stupid, memory decrease etc. the incidence rate of the linger effect distinguish to 78% and 82.7%, set the comparison didn’t show Zhao difference.
3 discussions
Should arouse sex ulcer to mean that the patient is suffer each kind of wound(include big surgical operation), heavy disease and other in response to under the intense emotion condition appear stomach 12 bowels to glue a film of debauched, ulcerate, Shen blood etc., the advanced case disease merges and should arouse sex ulcer greatly bleeds and its death rate is still 2 ］s at above 50% ［ .
The apoplexy erupt should arouse sex ulcer to bleed of the main mechanism be the Qiu brain lower part is damaged, or the pathological changes involve Qiu before the brain the area independent nerve center or brain stem pneumogastric nerves pit machine, pneumogastric nerves excitement, a great deal of B Mao Dan alkali make the stomach acid and stomach egg white Mao increase Gao, in great quantities release the adrenal glands skin quality vegetable in the meantime, injure stomach to glue film natural cover, sympathetic nerves tension change, the catechol An in blood density increase Gao, make the stomach wall afferent constringency, glue a film to lack blood, the stomach glues a film blood decrease and make the stomach glue film natural cover damaged aggravate, produce should arouse sex ulcer ［ 3 ］ .
The thunder Ni is for the D is a H2 to be subjected to the body Zu Zhi, can repress stomach acid to secrete, make thus damaged glue a film to quickly recover, and can increase stomach to glue a film blood, to should arouse appearance to descend stomach to glue a film blood decrease to have a protection function ［ is 4 ］s.This text data express that applied the thunder Ni should prevent apoplexy from combine arouse sex ulcer for the D, its incidence rate is 2% since low at the matched control, also low is 6.1% of the report way at Li3 Wei3 Wei3’s etc., the support thunder Ni has to lower the clinical effect that should arouse a sex ulcer incidence rate for the D, this death rate is for 25.49% and cure the set as 18.9% among them, matched control is 31.69%, treatment set the death rate be low the apoplexy death rate of the way is at the cultural heritage report is 5 ］s, compare with matched control to also obviously lower(P<0.01) for 30% ［s with 40% ～s, hint the thunder Ni is for the D can obviously lower an apoplexy to erupt the death that should arouse sex ulcer issue of blood.
Although erupt the basic treatment measure that should arouse sex to is still to the prevention and cure apoplexy aggressive control blood pressure, lower to press inside Lu, prevention and cure brain dropsy, add to use thunder Ni on this foundation can not only obviously lower an apoplexy a sufferer to erupt an incidence rate for bleed up the digest way, but also can change acute to expect for the D of prepare after
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