Some people said that the liver looks like one to fill blood’s soft bean curd. Although it is the human body is biggest, the most important internal organs, but also is very sometimes frail. Carries on the main organ which as the human body the medicine transforms, the liver regular session receives the medicine the injury.
Some material demonstrated that in the US, the medicine hepatitis approximately composes in hospital liver disease patient 5%, occupies the adult liver disease patient 10%.
But in China, increases unceasingly along with the medicine type, the new medicine widespread use, the medicine causes the case which the liver harms to be also common. Beijing University Clinical Pharmacology Research institute Assistant Manager Xiao Yonghong when accepts “Life Times” reporter the interview indicated that the medicine liver disease is neglected easily by the human, serious possibly endangers life.
Easy to injure the liver the drugs: The antibiotics and allays a fever the analgesic
Can cause the medicine type which the liver damages to be quite widespread. “even may say, so long as is the medicine, possibly is influential to the liver.”Xiao Yonghong said. And, the anti-tuberculosis medicine, like the rifampin, as well as allays a fever the analgesia class medicine, like the paracetamol and so on, injuries the liver to be fiercest. “this is decides by medicine’s characteristic. In metabolism process, the above medicine’s chemical composition will have the destructive effect to the liver cell. For example the anti-tuberculosis medicine and the metabolite have the strong affinity to the macro-molecule, will disturb or destroys these macro-molecules, if DNA and RNA normal metabolism, will thus cause the liver damage.”
Generally speaking, easy to cause the common medicine which the liver harms mainly to have the following several kinds: Allays a fever the analgesic, the antibiotics, to fall the carbohydrate, the endocrine system medication (for example female oral contraceptive, methyltestosterone, protein assimilation hormone, thyroid gland medicine and so on), the anti-tumor medicine (for example sulfur zuo purine, ammonia armor die ling and so on), the spirit class disease medication (for example wintermin, stable and so on), the anaesthetic. Also has a Chinese medicine, like Huang Yaozi, ma-huang, pass akebir quinata, fish gallbladder, medicine of seven ingredients and so on, also easy wound liver.
Most injuries the liver the medicine usage: Applies drugs jointly
Xiao Yonghong believed that each medicine harms liver’s concrete spot and the mechanism is different, if two medicines also affect, that liver difficulty with resists “the dual attack” radically, the damage probability is naturally bigger.
A quite typical example, is the cold remedy redundant use. Include including traditional Chinese medicine many cold remedies to the acetyl amino-phenol. This chemical composition has allays a fever the analgesia function. If simultaneously takes two kind of above cold remedies, will take in unconscious to the acetyl amino-phenol total quantity greatly will exceed the allowed figure. “or some tuberculosis adversity and the patient have caught cold, if uses at will allays a fever the analgesic, without doubt is adds on the new burden again for the frail liver
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